206 research outputs found

    Adults are more efficient in creating and transmitting novel signalling systems than children

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    Iterated language learning experiments have shown that meaningful and structured signalling systems emerge when there is pressure for signals to be both learnable and expressive. Yet such experiments have mainly been conducted with adults using language-like signals. Here we explore whether structured signalling systems can also emerge when signalling domains are unfamiliar and when the learners are children with their well-attested cognitive and pragmatic limitations. In Experiment 1, we compared iterated learning of binary auditory sequences denoting small sets of meanings in chains of adults and 5-7-year old children. Signalling systems became more learnable even though iconicity and structure did not emerge despite applying a homonymy filter designed to keep the systems expressive. When the same types of signals were used in referential communication by adult and child dyads in Experiment 2, only the adults, but not the children, were able to negotiate shared iconic and structured signals. Referential communication using their native language by 4-5-year old children in Experiment 3 showed that only interaction with adults, but not with peers resulted in informative expressions. These findings suggest that emergence and transmission of communication systems is unlikely to be driven by children, and point to the importance of cognitive maturity and pragmatic expertise of learners as well as feedback-based scaffolding of communicative effectiveness by experts during language evolution

    Study of enteroviruses in families in Lagos, Nigeria

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    A study of enteroviruses was carried out in 400 persons, making up 95 families in 15 residential areas of Lagos, Nigeria. The study period was November, 1962 to September, 1963. 1476 faecal specimens from the above persons were passed in primary cultures of monkey kidney, (cercopithecus aethiops tantalus). 238 viruses were isolated, of which 70 were typed as enteroviruses. 37 belonged to the polio group, 15 to the Coxsackie B group, and 18 were Echo viruses. A possible identity was found for some of the non-typable isolates by their association with typable isolates in families, residential areas and the community in general. The remainder were untyped by the methods used. The isolates were discussed in relation to their patterns in seasons, residential areas, and families, and their possible association with tribes, occupations and sexes. Their possible relationship to clinical disease in the community was evaluated, and the advisability of vaccination discussed. Alternative plans were described

    Role and regulation of hepatic 11β-hydroxysteroid dehydrogenase type 1

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    Gaining Balance: Toward a Grounded Theory of the Decision-Making Processes of Applicants for Adoption of Children with and without Disabilities

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    A grounded theory is presented of the decision-making processes among applicants when considering available children with and without disabilities for domestic public adoption. Using grounded theory methodology (Strauss & Corbin, 1998), data from 15 adoption applicants were analyzed followed the traditional three coding phases. The central category of Adoption Decision Making is labeled Gaining Balance and was the underpinning concept to all categories and sub-categories (i.e., in parentheses) of the theory: Commitment (e.g., motivation, financial considerations), Persistence (e.g., coping with emotions, counteracting pessimism), and Evaluation (e.g., assessments of personal abilities and resources, assessments of knowledge of potential adoptees\u27 needs). The results are compared to existing literature and implications for child welfare practices and further research are discussed

    Development of a new scale to measure ambiguity tolerance in veterinary students

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    The ability to cope with ambiguity and feelings of uncertainty is an essential element of professional practice. Research with physicians has identified that intolerance of ambiguity or uncertainty is linked to stress and some authors have hypothesised that there could be an association between intolerance of ambiguity and burnout (e.g. Cooke et al 2013). We describe the adaptation of the TAMSAD (Tolerance of Ambiguity in Medical Students and Doctors) scale for use with veterinary students. Exploratory factor analysis supports a unidimensional structure for the Ambiguity tolerance construct. Although internal reliability of the 29 item TAMSAD scale is reasonable (α = 0.50), an alternative 27 item scale (drawn from the original 41 items used to develop TAMSAD) shows higher internal reliability for veterinary students (α = 0.67). We conclude that there is good evidence to support the validity of this latter TAVS (Tolerance of Ambiguity in Veterinary students) scale to study ambiguity tolerance in veterinary students

    Continental slope records indicate a grounded ice sheet margin during past glacials, South Shetland Trench, Antarctica

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    The South Shetland Trench (SST) is located around 100 km northwest, and parallel to, the South Shetland Islands, located between the Antarctic Peninsula and South America. Although a number of studies examining glacial history have been undertaken in the Bransfield Strait located between the South Shetland Islands and the Antarctic Peninsula to the south, the authors believe this is the first study of the seafloor glacial geomorphology, and recent glacial history of the SST. This paper presents the results from a Eurofleets2 expedition to the SST that took place in December 2015. There is evidence from other sub-Antarctic islands such as the South Orkney Islands and Elephant Island for glaciations that extended well onto their continental shelves although a lack of age constraint from marine cores means it cannot be tied to a specific glaciation. Multibeam echosounder data reveal the study area on the southern flank of the South Shetland Trench to host a system of linear downslope gullies and glacigenic debris flows. Downslope gullies have been observed on other glaciated margins such as the Scotian slope offshore Canada, Ross Sea Antarctica, north-western Barents Sea and West Shetland Margin offshore north-western UK. The gullies are inferred as being eroded by turbidity currents comprising cold, dense, sediment-rich meltwater released from an ice front located at or near the continental shelf break. Glacigenic debris flows are found to extend from the continental shelf break to the lower continental slope. Sub-bottom profiler data penetrated up to 150ms below seafloor in places and reveal a stacked sequence of debris flows suggestive of a fluctuating ice front that was grounded to, and retreated from, the shelf break on several occasions. The trench floor appears to be devoid of major geomorphological features as revealed by the multibeam echosounder data and comprise a relatively well layered sequence imaged by the sub-bottom profiler. In addition 3 gravity cores up to 2.79 m in length and one core catcher sample were recovered from the study area. The cores will be analysed on their return to the UK and combined with the acoustic data to produce a shallow geological model specifically looking at the fluctuating ice margin located north of the South Shetland Islands

    Thiamin and Riboflavin in Human Milk: Effects of Lipid-Based Nutrient Supplementation and Stage of Lactation on Vitamer Secretion and Contributions to Total Vitamin Content

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    While thiamin and riboflavin in breast milk have been analyzed for over 50 years, less attention has been given to the different forms of each vitamin. Thiamin-monophosphate (TMP) and free thiamin contribute to total thiamin content; flavin adenine-dinucleotide (FAD) and free riboflavin are the main contributors to total riboflavin. We analyzed milk collected at 2 (n = 258) or 6 (n = 104), and 24 weeks (n = 362) from HIV-infected Malawian mothers within the Breastfeeding, Antiretrovirals and Nutrition (BAN) study, randomly assigned at delivery to lipid-based nutrient supplements (LNS) or a control group, to investigate each vitamer’s contribution to total milk vitamin content and the effects of supplementation on the different thiamin and riboflavin vitamers at early and later stages of lactation, and obtain insight into the transport and distribution of these vitamers in human milk. Thiamin vitamers were derivatized into thiochrome-esters and analyzed by high-performance liquid-chromatography-fluorescence-detection (HPLC-FLD). Riboflavin and FAD were analyzed by ultra-performance liquid-chromatography-tandem-mass-spectrometry (ULPC-MS/MS). Thiamin-pyrophosphate (TPP), identified here for the first time in breast milk, contributed 1.9–4.5% to total thiamin. Free thiamin increased significantly from 2/6 to 24 weeks regardless of treatment indicating an active transport of this vitamer in milk. LNS significantly increased TMP and free thiamin only at 2 weeks compared to the control: median 170 versus 151μg/L (TMP), 13.3 versus 10.5μg/L (free thiamin, p<0.05 for both, suggesting an up-regulated active mechanism for TMP and free thiamin accumulation at early stages of lactation. Free riboflavin was consistently and significantly increased with LNS (range: 14.8–19.6μg/L (LNS) versus 5.0–7.4μg/L (control), p<0.001), shifting FAD:riboflavin relative amounts from 92–94:6–8% to 85:15%, indicating a preferred secretion of the free form into breast milk. The continuous presence of FAD in breast milk suggests an active transport and secretion system for this vitamer or possibly formation of this co-enymatic form in the mammary gland

    Differences between international recommendations on breastfeeding in the presence of HIV and the attitudes and counselling messages of health workers in Lilongwe, Malawi

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    BACKGROUND: To prevent postnatal transmission of HIV in settings where safe alternatives to breastfeeding are unavailable, the World Health Organization (WHO) recommends exclusive breastfeeding followed by early, rapid cessation of breastfeeding. Only limited data are available on the attitudes of health workers toward this recommendation and the impact of these attitudes on infant feeding counselling messages given to mothers. METHODS: As part of the Breastfeeding, Antiretroviral, and Nutrition (BAN) clinical trial, we carried out an in-depth qualitative study of the attitudes, beliefs, and counselling messages of 19 health workers in Lilongwe, Malawi. RESULTS: Although none of the workers had received formal training, several reported having counseled HIV-positive mothers about infant feeding. Health workers with counselling experience believed that HIV-infected mothers should breastfeed exclusively, rather than infant formula feed, citing poverty as the primary reason. Because of high levels of malnutrition, all the workers had concerns about early cessation of breastfeeding. CONCLUSION: Important differences were observed between the WHO recommendations and the attitudes and practices of the health workers. Understanding these differences is important for designing effective interventions
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